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Ketamine Therapy for PTSD in Jacksonville, FL

Carrying the weight of trauma affects your daily wellbeing

PTSD can manifest in many ways — hypervigilance, flashbacks, emotional numbness, disrupted sleep. If these symptoms persist despite other treatments, ketamine therapy may provide meaningful support as part of a comprehensive care plan.

Learn more →
Ketamine for PTSD at The Practice in Jacksonville, FL

About this treatment

Ketamine-assisted support for PTSD

Ketamine may help reduce PTSD symptoms by affecting glutamate pathways involved in trauma processing and emotional regulation. Our trauma-informed team provides care in a safe, supportive environment. Treatment is most effective as part of a comprehensive plan that may include therapy and other supportive services.

Why patients choose us

What makes our care different

Ketamine may help reduce PTSD symptoms by affecting glutamate pathways involved in trauma processing and emotional regulation. Our trauma-informed team provides care in a safe, supportive environment. Treatment is most effective as part of a comprehensive plan that may include therapy and other supportive services.

Personalized Approach

Every treatment plan is tailored to your unique needs, goals, and clinical profile.

Expert Care Team

Our providers are trained in the latest evidence-based approaches to your care.

Comprehensive Evaluation

Thorough assessment to understand your complete health picture.

Ongoing Support

We provide continuous care and monitoring throughout your treatment journey.

Integrated Services

Access to multiple specialties under one roof for coordinated care.

Comfortable Environment

Our San Marco clinic is designed to be welcoming, calm, and supportive.

What to expect

Your path, step by step

  1. 01

    Book Your Consult

    Choose the service that matches your goals and schedule a consultation.

  2. 02

    Meet With Our Team

    Discuss your symptoms, history, and treatment options with our clinical team.

  3. 03

    Receive a Personalized Plan

    Your care path is tailored to your needs, eligibility, and clinical recommendations.

  4. 04

    Begin Care With Support

    Move forward with a clear plan and ongoing support from The Practice team.

This may be a fit if you…

  • Adults seeking personalized, evidence-based care
  • Those looking for a comprehensive, whole-person approach
  • Patients willing to engage in an initial consultation
  • Individuals seeking compassionate, professional healthcare

It may not be right if you…

  • Those seeking emergency or acute crisis care (please call 911)
  • Individuals unable to participate in the consultation process
  • Certain medical conditions may require clearance from your primary physician

What the research shows

IV ketamine vs. Spravato

Systematic reviews of separate controlled trials have reported larger pooled short-term effects for IV ketamine on several measures. These are indirect comparisons — direct head-to-head evidence remains limited.

Key — how to read the numbers

RR
Relative Risk — how many times more likely patients were to improve on the treatment than on a placebo (a dummy treatment). Example: RR 3.0 means about 3× more likely to respond. Higher is better.
Hedges’ g
A research score for how big the improvement was, not just whether it happened. Rough guide: ~0.2 = small, ~0.5 = medium, ~0.8 or higher = large. Higher is better.
NNT
Number Needed to Treat — how many people need this treatment for one extra person to improve compared with placebo. Example: NNT 3 means treat 3 people for one additional good outcome. Lower is better.

Response compared with placebo

Pooled relative likelihood of a clinically meaningful reduction in depression symptoms

Bahji et al. (2021)

IV Ketamine

RR 3.01

Larger pooled relative effect

Spravato

RR 1.38

Remission compared with placebo

Pooled relative likelihood of reaching few or no remaining depression symptoms

Bahji et al. (2021)

IV Ketamine

RR 3.70

Larger pooled relative effect

Spravato

RR 1.47

Pooled symptom improvement

Standardized effect size across separate controlled trials; study designs and populations varied.

Seshadri et al. (2024)

IV Ketamine

Hedges’ g 1.52

Larger pooled effect size

Spravato

Hedges’ g 0.31

Number needed to treat (NNT)

Lower NNT means fewer people need treatment for one additional person to respond compared with placebo.

Calder et al. (2024)

IV Ketamine

✓ NNT 3 from day 1 to week 1; NNT 9 at 4 weeks

Spravato

— NNT 2 at day 1; NNT 11 at 4 weeks

Sources: Bahji et al. (2021) Seshadri et al. (2024) Calder et al. (2024) . Figures are relative effects versus placebo or pooled effect sizes from systematic reviews and meta-analyses of depression trials.

Individual results vary. Ketamine therapy is not appropriate for everyone — candidacy is determined during a comprehensive psychiatric evaluation.

Invest in your mind

Flexible options designed for rapid relief and lasting change

6-Pack Series

$449 per infusion

Most common starting protocol

  • Six infusions over about 4 weeks
  • Private infusion room, every visit
  • Board-certified psychiatric provider
  • Continuous vitals monitoring
Popular

10-Pack Series

$399 per infusion

Best value for extended care

  • Ten infusions — induction plus maintenance
  • Private infusion room, every visit
  • Board-certified psychiatric provider
  • Continuous vitals monitoring

Single Booster Infusion

$549 per infusion*

For returning patients

  • One infusion at your established dose
  • Private infusion room
  • Board-certified psychiatric provider
  • Continuous vitals monitoring

Pricing applies to ketamine infusions for depression, anxiety, and PTSD. Infusions for chronic pain are priced separately — pain protocols require nearly three times the treatment time.

Package pricing represents per-infusion cost when purchased as a series. Financing options available — ask during your consultation.

*Only clients who have already completed an induction protocol (6 infusions in 4 weeks) with The Practice may book single infusions.

See the full cost breakdown — financing, insurance & Spravato comparison →

Common questions

What patients ask about Ketamine for PTSD

How can ketamine help with PTSD symptoms?

Ketamine may help reduce PTSD symptoms by affecting glutamate pathways in the brain related to trauma processing. Many patients report reduced hypervigilance and improved emotional regulation.

Is ketamine a cure for PTSD?

Ketamine is not a cure, but it may provide significant symptom relief. It is most effective as part of a comprehensive treatment plan that may include therapy and other supports.

What does a PTSD-focused session involve?

Sessions take place in a calm, safe environment. Our team is trained in trauma-informed care and ensures you feel comfortable throughout the experience.

Can ketamine help with complex trauma?

Many patients with complex trauma histories have found ketamine helpful. A thorough consultation helps determine if it is appropriate for your specific needs.

Will I have to talk about my trauma during the session?

No. Unlike therapy, ketamine sessions do not require you to discuss traumatic experiences. The medicine works at a neurobiological level.

How is this different from EMDR or traditional therapy?

Ketamine works through neurochemical mechanisms rather than psychological processing. Many patients find it complements their ongoing therapy work.

What follow-up support is available?

We recommend integrating ketamine treatment with ongoing therapy. Our team can help coordinate care with your therapist or refer you to one of ours.

Are there any risks for people with PTSD?

Our team conducts a thorough screening to ensure ketamine is safe for you. We discuss all potential risks and benefits during your consultation.

Find out if ketamine for ptsd is right for you

For a limited time, ketamine consultations are free — in person or via Zoom. Get your questions answered by our clinical team at no cost.