Limited-time offer: ketamine consultations are currently FREE — normally $49. In person or via Zoom.
Veteran? See how the VA covers ketamine treatment — read our guide.
Ketamine Infusion Therapy in Jacksonville, FL
When other treatments have not brought the relief you need
If you have tried multiple medications or therapies without significant improvement, ketamine infusions may offer a different approach. Many patients seeking ketamine therapy in Jacksonville have experienced treatment-resistant symptoms that impact their daily lives, relationships, and sense of wellbeing.
Clinically guided care San Marco, Jacksonville Personalized protocols
About this treatment
Clinically guided ketamine infusion therapy
Ketamine is an FDA-approved anesthetic that, when administered at lower than anesthetic doses in a controlled medical setting, may help with treatment-resistant depression, anxiety, PTSD, and certain pain conditions. Our infusions are only administered by advanced practice nurse practitioners who are board-certified in psychiatry or a board-certified psychiatrist in a comfortable, monitored environment. Treatment protocols are personalized based on your consultation, symptoms, and clinical needs.
Why patients choose us
Ketamine is an FDA-approved anesthetic that, when administered at lower than anesthetic doses in a controlled medical setting, may help with treatment-resistant depression, anxiety, PTSD, and certain pain conditions. Our infusions are only administered by advanced practice nurse practitioners who are board-certified in psychiatry or a board-certified psychiatrist in a comfortable, monitored environment. Treatment protocols are personalized based on your consultation, symptoms, and clinical needs.
Rapid Symptom Relief
Some patients report improvements within hours to days, unlike traditional medications that may take weeks.
Treatment-Resistant Cases
Designed for those who have not found adequate relief from other treatments.
Monitored Sessions
Every infusion is supervised by board-certified psychiatric providers in a controlled medical environment.
Personalized Protocols
Treatment plans are tailored to your specific symptoms, history, and clinical needs.
Multiple Applications
May help with depression, anxiety, PTSD, and certain chronic pain conditions.
Supportive Environment
Our clinic is designed to be calming, comfortable, and conducive to healing.
What to expect
Your path, step by step
-
01
Book Your $49 Consult
Choose the service that matches your goals and schedule a consultation.
-
02
Meet With Our Team
Discuss your symptoms, history, and treatment options with our clinical team.
-
03
Receive a Personalized Plan
Your care path is tailored to your needs, eligibility, and clinical recommendations.
-
04
Begin Care With Support
Move forward with a clear plan and ongoing support from The Practice team.
This may be a fit if you…
- Adults seeking personalized, evidence-based care
- Those looking for a comprehensive, whole-person approach
- Patients willing to engage in an initial consultation
- Individuals seeking compassionate, professional healthcare
It may not be right if you…
- Those seeking emergency or acute crisis care (please call 911)
- Individuals unable to participate in the consultation process
- Certain medical conditions may require clearance from your primary physician
What the research shows
IV ketamine vs. Spravato
Across head-to-head systematic reviews and meta-analyses (2020–2024), IV ketamine consistently outperformed the esketamine nasal spray on every major measure.
Chance of meaningful relief
How much more likely patients were to see their symptoms cut in half, compared to placebo
Bahji et al., J Affect Disord 2021 (RR 3.01 vs 1.38)
3× more likely
More than twice the benefit of the nasal spray
1.4× more likely
Chance of remission
How much more likely patients were to reach few or no remaining symptoms, compared to placebo
Bahji et al., J Affect Disord 2021 (RR 3.70 vs 1.47)
3.7× more likely
About 2.5× the benefit of the nasal spray
1.5× more likely
Size of the improvement
How much symptoms improved in head-to-head studies. Researchers consider anything above 0.8 a large effect.
Seshadri et al., J Affect Disord 2024 (Hedges' g)
1.52 — very large
Nearly five times the measured improvement
0.31 — small
Compared to typical antidepressants
How each stacks up against everyday medications like SSRIs
Fountoulakis et al., Am J Psychiatry 2025; Nikolin et al., eClinicalMedicine 2023
✓ Roughly double the effect of typical antidepressants
— About the same as typical antidepressants
How well the benefit lasts
Whether patients were still feeling better a month after treatment
Calder et al., J Affect Disord 2024 (NNT 3→9 vs 2→11)
✓ Benefit holds up well at 4 weeks
— Strong at first, but fades faster
Relief from suicidal thoughts
How long measurable relief lasted in studies
Shen et al., Transl Psychiatry 2024; Wang et al., Clin Psychopharm Neurosci 2021
✓ Within a day — still measurable nearly 4 weeks later
— A few hours — no longer measurable by the next day
Sticking with treatment
How many patients stopped treatment early in studies
Bahji et al., J Affect Disord 2021
✓ More patients completed treatment
— 80% more patients dropped out
Sources: Bahji et al., J Affect Disord 2021 · Seshadri et al., J Affect Disord 2024 · Calder et al., J Affect Disord 2024 · Nikolin et al., eClinicalMedicine 2023 · Shen et al., Transl Psychiatry 2024 · Wang et al., Clin Psychopharmacol Neurosci 2021 · Fountoulakis et al., Am J Psychiatry 2025. Figures are relative risk vs. placebo and pooled effect sizes from systematic reviews and meta-analyses of randomized trials in depression.
Individual results vary. Ketamine therapy is not appropriate for everyone — candidacy is determined during a comprehensive medical consultation.
Invest in your mind
Flexible options designed for rapid relief and lasting change
6-Pack Series
$429 per infusion
Most common starting protocol
10-Pack Series
$399 per infusion
Best value for extended care
Single Booster Infusion
$549 per infusion*
For returning patients
Package pricing represents per-infusion cost when purchased as a series. Financing options available — ask during your consultation.
*Only clients who have already completed an induction protocol (6 infusions in 4 weeks) with The Practice may book single infusions.
Common questions
What patients ask about Ketamine Therapy
What conditions can ketamine therapy help with?
Ketamine therapy may help with treatment-resistant depression, anxiety, PTSD, and certain chronic pain conditions. Eligibility is determined through a comprehensive consultation with our clinical team.
What does a ketamine infusion session feel like?
Most patients describe a relaxed, dream-like state. You remain conscious throughout the session in a comfortable, monitored setting. Our team ensures you feel safe and supported at every step.
How many sessions are typically needed?
Treatment protocols vary by individual. Many patients begin with a series of sessions, followed by maintenance treatments. Your specific plan is personalized during your consultation.
Is ketamine therapy safe?
Ketamine has been used safely in medical settings for decades. Our infusions are only administered by advanced practice nurse practitioners who are board-certified in psychiatry or a board-certified psychiatrist, in a controlled, monitored environment with appropriate safety protocols.
How should I prepare for my infusion?
You will receive detailed preparation instructions before your first session. Generally, we recommend avoiding food for a few hours beforehand and arranging transportation home.
Are there any side effects?
Some patients may experience mild, temporary effects such as drowsiness or nausea. Our team monitors you throughout and is prepared to manage any discomfort.
Will my insurance cover ketamine therapy?
Coverage varies by provider and plan. Our team can help you understand your options and provides documentation that may support insurance claims.
How soon might I notice results?
Some patients report feeling improvements within hours to days after their first session. Results vary by individual and condition being treated.
Related care
Find out if ketamine therapy is right for you
For a limited time, ketamine consultations are free — in person or via Zoom. Get your questions answered by our clinical team at no cost.