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Patient experiencing relief from chronic pain through ketamine infusion
Up to 70% of chronic neuropathic pain patients experience significant relief with ketamine infusion therapy

Break the cycle of chronic pain.

Traditional pain management often relies on opioids and nerve blocks — approaches that mask symptoms without addressing the underlying neurological dysfunction.

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Treatment Benefits

A Different Pathway to Pain Relief

If you've been told to 'just manage it' or you're tired of cycling through medications that dull your mind more than your pain, ketamine infusion therapy may be the reset your nervous system needs.

Neuropathic Pain Relief

Neuropathic Pain Relief

Ketamine directly modulates the NMDA receptors responsible for neuropathic pain — the burning, shooting, and tingling sensations caused by nerve damage that rarely respond to conventional painkillers.

Diabetic Neuropathy

Diabetic Neuropathy

For patients living with the progressive nerve pain of diabetes, ketamine infusions can reduce pain intensity and improve daily function when first-line treatments have stopped working.

Post-Surgical & Phantom Limb Pain

Post-Surgical & Phantom Limb Pain

Persistent pain after surgery or amputation often stems from central sensitization. Ketamine helps "reset" these pain circuits, offering relief that traditional approaches can't reach.

CRPS / RSD Relief

CRPS / RSD Relief

Complex Regional Pain Syndrome is one of the most debilitating chronic pain conditions — and one of the most responsive to ketamine therapy. Many CRPS patients report dramatic improvement after a structured infusion series.

Migraine & Chronic Headache

Migraine & Chronic Headache

For patients with treatment-resistant migraines or chronic daily headaches, ketamine infusions can break the cycle of pain that preventive medications and triptans haven't been able to touch.

Central Sensitization Reset

Central Sensitization Reset

Over time, chronic pain rewires your nervous system to amplify pain signals. Ketamine promotes neuroplasticity — helping your brain and spinal cord recalibrate and reduce that heightened pain response.

The Science

How Ketamine Treats Pain

Traditional pain management often masks symptoms. Ketamine works differently, targeting the central nervous system to interrupt pain signaling pathways and recalibrate your body's natural pain response.

01

NMDA Receptor Modulation

Ketamine blocks NMDA receptors in the brain and spinal cord — the same receptors responsible for "wind-up," the process that amplifies chronic pain signals over time.

02

Interrupting Central Sensitization

By quieting overactive pain circuits, ketamine reduces the heightened sensitivity that makes even light touch feel painful — a hallmark of neuropathic conditions.

03

Reducing Neuroinflammation

Ketamine has anti-inflammatory properties that calm the neuroinflammatory processes contributing to chronic pain states, particularly in conditions like CRPS and fibromyalgia.

04

Restoring Descending Inhibition

Your body has built-in pain-dampening pathways that chronic pain can suppress. Ketamine helps restore these natural inhibitory systems, improving your body's own ability to regulate pain.

05

Promoting Neuroplasticity

Ketamine stimulates the growth of new neural connections — essentially helping your nervous system rewire itself away from entrenched pain patterns and toward healthier signaling.

Your Treatment Timeline

Infusion Series
Structure

Our targeted pain protocol is designed to rapidly recalibrate your nervous system and provide sustained relief through a carefully structured series.

Assessment & Initiation

/Phase 1
Infusion 1-2

Your first infusions establish your response to ketamine. We carefully titrate your dose, monitor your comfort, and assess how your pain levels respond. Many patients notice improvement within the first one to two sessions.

Building Relief

/Phase 2
Infusion 3-4

As infusions build on each other, pain relief deepens and lasts longer between sessions. We fine-tune your protocol based on your response, optimizing for maximum benefit.

Consolidation

/Phase 3
Infusion 5+

Later infusions consolidate your gains. The goal is sustained relief that extends well beyond your infusion series, with many patients reporting weeks to months of improved function.

Maintenance Phase

Some patients benefit from periodic booster infusions — typically every 4–8 weeks — to maintain their results. We'll work with you to find the schedule that keeps your pain managed long-term.

Long-term Management
Serene background for Pain CTA

A Different Pathway to True Pain Relief

If you’ve tried treatment after treatment and continue to feel limited, exhausted, and restricted by pain, it can start to feel like nothing will ever change.

But chronic pain doesn’t mean your body is broken—it means you deserve a different approach.

Request a Consultation
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Why Choose Us

Why The Practice

Ketamine infusion therapy is only as good as the team behind it. At The Practice, your infusions are administered under the supervision of board-certified providers who understand pain — not just as a symptom to suppress, but as a complex neurological condition that deserves expert, individualized care.

We're not a ketamine-only clinic. As an integrated psychiatric and wellness practice, we treat the whole picture — combining ketamine therapy with complementary services like psychiatric care, hormone optimization, and regenerative medicine to address every factor contributing to your pain.

Expert Medical Care

  • Board-certified psychiatric and medical providers
  • Individualized dosing protocols — not one-size-fits-all
  • Continuous vital sign monitoring during infusions
  • Deep understanding of complex neurological pain

Boutique Experience

  • Comfortable, private infusion suites
  • Veteran-owned small business committed to exceptional patient care
  • Relaxing environment optimized for healing

Holistic Wellness Integration

  • Integrated care model addressing mental health, hormones, and physical wellness
  • Regenerative medicine treatments
  • Complementary psychiatric care
Eligibility

Is This Right For You?

Ideal Candidates

  • Chronic neuropathic pain that hasn't responded adequately to conventional treatments
  • Diabetic neuropathy with persistent symptoms despite medication management
  • Complex Regional Pain Syndrome (CRPS/RSD)
  • Post-surgical pain or phantom limb pain
  • Chronic migraine or daily headache disorders resistant to preventive therapy
  • Patients seeking an alternative to long-term opioid use
  • Central sensitization syndromes

May Not Be Suitable

  • Uncontrolled hypertension
  • Active substance use disorder
  • History of psychosis or schizophrenia
  • Certain cardiac conditions
  • Pregnancy
  • Untreated hyperthyroidism

A thorough consultation is required to determine eligibility. Our medical team will review your health history and discuss your goals to create a personalized treatment plan.

Investment in Relief

Flexible options designed to provide rapid relief and lasting change for your pain.

Single Infusion

$849/ per infusion

Package Pricing billing

  • 4 hour ketamine infusion for Pain
  • Vital sign monitoring throughout
  • Post-infusion recovery and assessment

Ideal for booster treatments or initial trial.

3-Pack Series

$799/ per infusion

Package Pricing billing

  • 3 - 4 hour infusions for pain
  • Personalized dosing protocol
  • Progress tracking between sessions

A solid introduction to the benefits of our structured infusion protocol.

Popular

6-Pack Series

$749/ per infusion

Package Pricing billing

  • 6 - 4 hour infusions for pain
  • Full treatment series for optimal results
  • Personalized dosing and protocol adjustments
  • Best value for sustained relief

Full treatment series for optimal results.

Financing available through CareCredit.
Free Resource

Patient Guidebook

Download our comprehensive guide to ketamine therapy. Everything you need to know about preparation, what to expect, and how to maximize your treatment results.

  • What to expect during your infusion
  • Pre-treatment preparation checklist
  • Post-treatment care instructions
  • Frequently asked questions
  • Integration tips for lasting results
Download Patient Guidebook
Ketamine Infusion Therapy Patient Guide

Patient Guide

Ketamine
Infusion
Therapy

The Practice
Common Questions

Frequently Asked Questions

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Ketamine Therapy Background

Ready to Start Your Ketamine for Pain Journey?

Take the first step towards transformation. Schedule a consultation with our expert team to discuss your goals and create a personalized treatment plan.

Call (904) 877-1100

Same Week

Availability

Flexible

Payment Plans

The Practice

A sanctuary for holistic wellness, combining modern medicine with compassionate care in the heart of Jacksonville.

SBA Veteran-Owned Certified

Services

  • Ketamine Infusions for Depression
  • Ketamine Infusions for Pain
  • Aesthetics
  • Primary Care
  • Psychiatry
  • Psychotherapy
  • Men's Health
  • Women's Health
  • Weight Loss
  • Ketamine Infusion Certification
  • Vampire Procedures Certification

Contact

  • 📍San Marco
    Jacksonville, FL
  • ✉️info@thepractice.co
  • 📞(904) 877-1100
  • 📠(904) 877-1200

Hours

  • Mon - Thu10am - 5pm
  • FridayBy Appt
    Infusions, Therapy & Aesthetics
  • Sat - SunClosed
CareCredit Financing

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