Ketamine Therapy FAQ — Jacksonville, FL

Every question, answered honestly

22 of the questions patients actually ask us — about the treatment, the experience, the cost, and the safety — grouped so you can jump straight to what you need.

Patient resting comfortably during a monitored ketamine infusion at The Practice in Jacksonville

Looking for the full guide to ketamine infusions in Jacksonville — conditions, research, and booking? Start on our main page: Ketamine Infusion Therapy at The Practice.

The basics

What ketamine therapy is

What is ketamine therapy?

Ketamine therapy uses low, carefully controlled IV doses of ketamine — an FDA-approved anesthetic used safely in hospitals for over fifty years — to relieve symptoms of treatment-resistant depression, anxiety, PTSD, and certain chronic pain conditions. At sub-anesthetic doses it can produce meaningful mood improvement within hours to days rather than the weeks traditional antidepressants take.

What conditions does The Practice treat with ketamine?

Treatment-resistant depression, anxiety disorders, PTSD, and chronic pain conditions such as CRPS, neuropathy, and migraines. Suitability for your specific situation is determined at a consultation with our board-certified psychiatric team.

How is IV ketamine different from Spravato?

IV ketamine is the full racemic molecule delivered by infusion and used off-label for mood conditions; Spravato (esketamine) is a nasal spray containing only the S-molecule, FDA-approved for treatment-resistant depression and more commonly covered by insurance. Our ketamine vs. Spravato page compares them in depth.

Is ketamine just a party drug?

No. Recreational misuse involves uncontrolled doses in unsafe settings. Clinical ketamine is a precisely dosed, provider-monitored medical treatment administered in a controlled environment — the same medicine hospitals have relied on as an anesthetic for decades, at a fraction of anesthetic doses.

Treatment & experience

What treatment is like

What does a ketamine infusion feel like?

Most patients describe a relaxed, dream-like or floating state. Some experience mild dissociation — a temporary sense of detachment that fades within about an hour — while many feel little beyond deep relaxation. You stay conscious, can speak at any time, and are monitored continuously in a private room.

How long does each session take?

Plan for about two hours door to door: check-in and vitals, a roughly 40-minute infusion for mood conditions, and a monitored recovery period. Chronic-pain protocols use substantially longer infusions. Our what-to-expect page walks through the visit hour by hour.

How many infusions will I need?

The standard starting protocol is an induction series of six infusions over about four weeks. Patients who respond often continue with occasional single booster infusions to maintain the benefit. Your exact plan is personalized at your consultation.

How fast does ketamine work?

Many patients notice improvement within hours to days of their first infusion — one of ketamine’s most distinctive advantages over traditional antidepressants, which typically need four to six weeks. Response is tracked across your induction series; individual results vary.

Can I drive myself home?

No. You must arrange a ride home after every infusion, and we recommend taking the rest of the day off. Most patients feel back to baseline within a few hours and resume normal activities the next day.

Cost, insurance & financing

What it costs

How much does ketamine therapy cost in Jacksonville?

At The Practice, infusions for depression, anxiety, and PTSD cost $399–$549 each depending on how you book: $479 per infusion in the 6-pack induction series ($2,874 total), $399 in the 10-pack ($3,990 total), or $549 for a single booster. Prices are all-inclusive — provider, private room, and monitoring. Chronic-pain protocols are quoted separately because they require nearly three times the treatment time.

Does insurance cover ketamine infusions?

Usually not — IV ketamine is used off-label for mood conditions, so most plans decline it. We provide an itemized superbill you can submit for possible out-of-network reimbursement. Spravato, the FDA-approved nasal spray, is more commonly covered; if that is your better financial path, we will say so.

Do you offer financing?

Yes — we accept CareCredit, which splits treatment into monthly payments, and package pricing lowers the per-infusion cost. Many patients also use pre-tax HSA or FSA funds.

How much is the ketamine consultation?

Ketamine consultations are $49, in person at our San Marco clinic or via Zoom. If you are a candidate and move forward with treatment, the $49 is applied toward your care. If you are not a suitable candidate, the $49 is refunded in full. Either way, you leave with an honest recommendation and an exact written cost before committing to anything.

Does the VA cover ketamine for veterans?

The VA covers Spravato for veterans meeting treatment-resistant depression criteria, and in limited cases may authorize IV ketamine through Community Care. As a veteran-owned clinic we wrote a dedicated guide — see Ketamine & the VA for the step-by-step process.

Safety

Safety & side effects

Is ketamine therapy safe?

In a monitored clinical setting with trained providers, ketamine has a strong safety profile built on five decades of medical use. At The Practice every infusion is administered by a board-certified psychiatric provider or psychiatrist with continuous blood pressure, heart rate, and oxygen monitoring in a private room.

What are the side effects?

The common ones are mild and short-lived: dream-like dissociation, dizziness, nausea, a temporary rise in blood pressure, or headache — typically resolving within an hour or two of the session. Your provider monitors you throughout and can treat discomfort immediately.

Who should not get ketamine therapy?

Ketamine may not be appropriate for people with uncontrolled high blood pressure, certain heart conditions, active psychosis, a history of substance misuse, or pregnancy. That is exactly what the medical evaluation screens for — candidacy is confirmed before any treatment is scheduled.

Is ketamine addictive?

In a controlled clinical protocol — precise low doses, spaced sessions, provider oversight, no take-home medication — the risk profile is very different from recreational misuse. We screen for substance-use history during evaluation and monitor throughout care.

Getting started

Booking & your first visit

How do I get started with ketamine therapy in Jacksonville?

Book a $49 consultation — online or by calling (904) 877-1100 — in person at our San Marco clinic or via Zoom. Our psychiatric team reviews your history and goals and tells you honestly whether ketamine is a fit.

What should I bring to the consultation?

A list of current medications, the antidepressants or treatments you have tried (with doses and durations if you know them), and any relevant medical records. The more history you bring, the more precise the recommendation.

Where is The Practice located?

At 3547 Hendricks Ave in Jacksonville’s San Marco district, serving patients from across Northeast Florida — including Ponte Vedra, Orange Park, and St. Augustine. We are veteran-owned and LegitScript certified.

How soon can I start treatment?

Consultations are typically available the same week, and qualifying patients can often begin their induction series shortly after. There are no long wait lists.

Still have a question?

Ask a human — $49 consult

The fastest way to get answers specific to your situation is a consultation with our clinical team. It's $49 — applied toward treatment if you're a candidate, fully refunded if not. In person or via Zoom.

Call (904) 877-1100

The ketamine resource center

Keep exploring ketamine therapy

Ketamine Infusion Therapy →

The main guide to IV ketamine at The Practice — conditions, research, and booking.

Treatment-Resistant Depression →

When two or more antidepressants haven’t worked — what ketamine offers TRD.

Ketamine for Anxiety →

Rapid relief for persistent anxiety, panic, and nervous-system activation.

Ketamine for PTSD →

Trauma-informed infusion care for hypervigilance and flashbacks.

Ketamine for Chronic Pain →

CRPS, neuropathy, migraines, and centralized pain protocols.

Cost & Pricing →

Transparent pricing: $399–$549 per infusion, financing, and insurance notes.

Ketamine vs. Spravato →

How IV ketamine and the FDA-approved nasal spray compare on results and cost.

What to Expect →

Your first infusion, hour by hour — preparation, the experience, and recovery.

How It Works →

The science: the glutamate surge and the dendritic spine regrowth seen in research.

What Is Ketamine Therapy? →

The complete beginner’s guide: history, mechanism, safety, and evidence.

Veterans & the VA →

How VA coverage works for Spravato and IV ketamine, and the Community Care path.

Side Effects & Safety →

What to expect: nausea, dizziness, dissociation, blood pressure — and who shouldn’t use ketamine.

The Experience →

Does ketamine get you high? Honest answers about what an infusion actually feels like.

Preparation Guide →

What to eat, what to avoid, what to bring, and how to set yourself up for the best experience.

Aftercare Guide →

First 24 hours, the week after, and how to maximize the neuroplasticity window.

Treatment Protocol →

The standard 6-infusion induction series, why a series matters, and maintenance scheduling.

Ketamine for OCD →

For obsessive-compulsive disorder: how ketamine’s glutamate mechanism may interrupt the OCD loop.

Ketamine for Bipolar Depression →

When antidepressants can’t be used — how ketamine differs for bipolar patients on mood stabilizers.

Ketamine vs. ECT →

How IV ketamine compares to electroconvulsive therapy — efficacy, side effects, and logistics.

Success Rates & Evidence →

What the research actually shows: response rates, remission rates, and what the numbers mean.

Patient Stories →

Real patient experiences with ketamine therapy at The Practice — depression, PTSD, and chronic pain.