Ketamine Infusion Cost in Jacksonville, FL
Real prices, published for everyone
No "call for pricing." No surprise facility fees. Ketamine infusions at The Practice cost $399–$549 per infusion, depending on how you book — and every price on this page includes your provider, a private room, and continuous monitoring.
The short answer
$399–$549 per infusion, all-inclusive
- 6-pack induction series $479 /infusion
- 10-pack series (best value) $399 /infusion
- Single booster (returning patients) $549 /infusion
- Consultation $49 applied toward treatment if you continue
CareCredit financing accepted · HSA/FSA eligible for most plans · Superbill provided for out-of-network insurance claims.
Pricing applies to infusions for depression, anxiety, and PTSD. Chronic-pain protocols are quoted separately.
How we compare
Below the typical national range — without cutting corners
Across the U.S., IV ketamine infusions for mood conditions commonly run from several hundred to about a thousand dollars each, and many clinics add separate consultation or facility fees on top. Our pricing stays at the lower end of that range and is all-inclusive.
The Practice — Jacksonville, San Marco
$399–$549
All-inclusive · $49 consult (applied toward treatment if you continue)
Typical U.S. ketamine clinics
$400–$1,000+
Consultation, booking, and facility fees often billed separately
Financing & payment options
Three ways to make treatment more affordable
01
CareCredit financing
We accept CareCredit, the healthcare credit card, so you can spread treatment across manageable monthly payments. Apply before your visit or ask about it at your consultation.
02
Package pricing
Series pricing brings each infusion down to $399–$479 — up to 27% less than our single-infusion rate. You pay for a defined series, not an open-ended subscription.
03
HSA & FSA funds
Many patients pay with pre-tax HSA or FSA dollars. Physician-supervised ketamine treatment generally qualifies as a medical expense — confirm the details with your plan administrator.
Insurance, honestly
Where insurance fits — and where it doesn't
Why plans rarely cover IV ketamine
Ketamine is FDA-approved as an anesthetic, and physicians prescribe it off-label for depression, anxiety, PTSD, and chronic pain. Because the mood indication is off-label, most insurance plans decline to cover IV infusions — which is why nearly every ketamine clinic in the country, including ours, is self-pay.
The insurance-covered alternative is Spravato (esketamine), the FDA-approved nasal spray for treatment-resistant depression. If that's the better financial path for you, we'll say so at your consultation.
How we help you claim what you can
- An itemized superbill after treatment that you can submit to your insurer for possible out-of-network reimbursement
- Clinical documentation and records that may support an insurance claim or appeal
- Records and medical-necessity letters that can support a VA Community Care request you initiate through your VA provider
- Straight answers about coverage at your consultation — before you spend anything
Reimbursement decisions always rest with your insurer and are never guaranteed.
Are you a veteran? The VA covers Spravato for treatment-resistant depression and, in limited cases, may authorize IV ketamine through Community Care. Read our practical guide: Ketamine treatment and the VA.
IV infusions vs. Spravato
Comparing the real cost of your two ketamine options
"Covered by insurance" doesn't always mean cheaper. Here's how the two treatments compare once copays, visit frequency, and monitoring time are counted.
| IV ketamine at The Practice | Spravato (esketamine) | |
|---|---|---|
| Typical cost to you | $399–$549 per infusion at The Practice — one transparent, self-pay price | Often insurance-covered for treatment-resistant depression; copays, deductibles, and clinic fees vary by plan |
| Insurance coverage | Rarely covered — IV ketamine is used off-label for mood conditions. We provide a superbill for possible out-of-network reimbursement. | FDA-approved for treatment-resistant depression, so it’s more commonly covered |
| Typical first month | Six infusions over about four weeks | Twice-weekly sessions during the first month |
| Time per visit | About 1–2 hours, including recovery | At least 2 hours of required post-dose monitoring per session, in a REMS-certified clinic |
| If you have no coverage | The prices published on this page are the full prices | Medication plus clinic and monitoring fees can add up quickly without insurance |
The bottom line: if your plan covers Spravato with a low copay, it may cost you less — and we'll tell you so. If you're paying cash or facing a high deductible, IV ketamine is often comparable or less expensive, with fewer visits in the first month. And price is only half the decision — the research comparison below shows how the two stack up clinically.
What the research shows
IV infusions vs. Spravato
Systematic reviews of separate controlled trials have reported larger pooled short-term effects for IV ketamine on several measures. These are indirect comparisons — direct head-to-head evidence remains limited.
Key — how to read the numbers
- Hedges’ g
- The research score behind our “small / large improvement” labels — it measures how big the improvement was, not just whether it happened. Rough guide: ~0.2 = small, ~0.5 = medium, ~0.8 or higher = large. Higher is better.
- NNT
- Number Needed to Treat — how many people need this treatment for one extra person to improve compared with placebo. Example: NNT 3 means treat 3 people for one additional good outcome. Lower is better.
Response compared with placebo
Pooled relative likelihood of a clinically meaningful reduction in depression symptoms
3× more likely
Larger pooled relative effect
1.4× more likely
Remission compared with placebo
Pooled relative likelihood of reaching few or no remaining depression symptoms
3.7× more likely
Larger pooled relative effect
1.5× more likely
Pooled symptom improvement
How much symptoms improved on average across separate controlled trials (Hedges’ g 1.52 vs. 0.31); study designs and populations varied.
Large improvement
Larger pooled effect size
Small improvement
Number needed to treat (NNT)
Lower NNT means fewer people need treatment for one additional person to respond compared with placebo.
✓ NNT 3 from day 1 to week 1; NNT 9 at 4 weeks
— NNT 2 at day 1; NNT 11 at 4 weeks
Sources: Bahji et al. (2021) Seshadri et al. (2024) Calder et al. (2024) . Figures are relative effects versus placebo or pooled effect sizes from systematic reviews and meta-analyses of depression trials.
Individual results vary. Ketamine therapy is not appropriate for everyone — candidacy is determined during a comprehensive psychiatric evaluation.
Cost questions, answered
What patients ask about ketamine pricing
How much does a ketamine infusion cost in Jacksonville?
At The Practice, ketamine infusions for depression, anxiety, and PTSD cost $399–$549 per infusion depending on how you book: $479 per infusion in a 6-pack induction series ($2,874 total), $399 per infusion in a 10-pack series ($3,990 total), or $549 for a single booster infusion for returning patients. Every price includes your provider, a private infusion room, and continuous monitoring — there are no facility fees or hidden add-ons.
Does this pricing apply to ketamine infusions for chronic pain?
No. The pricing on this page applies to ketamine infusions for depression, anxiety, and PTSD. Infusions for chronic pain conditions like CRPS and neuropathy are priced separately, because pain protocols require much longer sessions — nearly three times the treatment time of a mood-protocol infusion. You will receive an exact quote for your pain protocol during your consultation.
How much does a full course of ketamine treatment cost?
Most patients begin with an induction series of six infusions over about four weeks, which costs $2,874 at The Practice ($479 per infusion). Patients who continue with maintenance often choose the 10-pack at $3,990 ($399 per infusion). Your exact plan — and its exact cost — is confirmed at your consultation before you commit to anything.
Does insurance cover ketamine infusions?
Usually not. IV ketamine is used off-label for depression, anxiety, PTSD, and chronic pain, so most insurance plans decline to cover it. The Practice provides an itemized superbill and supporting documentation you can submit to your insurer for possible out-of-network reimbursement, though reimbursement is never guaranteed. Spravato (esketamine), the FDA-approved nasal spray, is more commonly covered by insurance.
Do you offer financing for ketamine treatment?
Yes. We accept CareCredit, which lets you split the cost of treatment into monthly payments. Package pricing also lowers the per-infusion cost to $399–$479. We walk through every payment option during your consultation.
Can I pay with HSA or FSA funds?
In most cases, yes. Physician-supervised ketamine treatment for a diagnosed condition generally qualifies as an eligible medical expense for HSA and FSA accounts. Check with your plan administrator to confirm your account’s rules.
How much is the ketamine consultation?
Consultations are $49 — not free — in person at our San Marco clinic or via Zoom. If you continue with treatment, the $49 is applied toward your care. The fee is refunded only if we determine you are not a candidate, not if you decline treatment. You’ll leave with an honest recommendation and an exact, written cost before any treatment begins.
Are there any hidden fees?
No. The per-infusion price includes your board-certified psychiatric provider, a private infusion room, continuous vitals monitoring, and post-infusion recovery time. We do not charge separate facility, booking, or monitoring fees.
Is IV ketamine or Spravato cheaper?
It depends on your insurance. If your plan covers Spravato with a low copay, Spravato may cost less out of pocket — though it typically requires twice-weekly visits with at least two hours of monitoring each during the first month. If you’re self-paying or have a high deductible, IV ketamine at $399–$549 per infusion is often comparable or less expensive. We’ll tell you honestly which path makes more financial sense for your situation during your consultation.
Coverage
Is ketamine covered by insurance?
IV ketamine infusions are usually not covered when used off-label for depression, anxiety, PTSD, or pain. Most Jacksonville patients self-pay, use HSA/FSA funds, or finance with CareCredit. We provide an itemized superbill for possible out-of-network reimbursement — never guaranteed.
Spravato (esketamine), the FDA-approved nasal spray for treatment-resistant depression, is more commonly covered by commercial plans and the VA for qualifying veterans. We offer IV ketamine only; if Spravato is clearly the better financial path, we will tell you honestly and help you understand next steps. Compare options on our infusions vs. Spravato page.
Ready for an exact written quote? Book a $49 consult or call (904) 877-1100. Full treatment details live on ketamine infusions in Jacksonville.
The ketamine resource center
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Treatment-Resistant Depression →
When two or more antidepressants haven’t worked — what ketamine offers TRD.
Ketamine for Anxiety →
Rapid relief for persistent anxiety, panic, and nervous-system activation.
Ketamine for PTSD →
Trauma-informed infusion care for hypervigilance and flashbacks.
Ketamine for Chronic Pain →
CRPS, neuropathy, migraines, and centralized pain protocols.
Infusions vs. Spravato →
How IV ketamine and the FDA-approved nasal spray compare on results and cost.
What to Expect →
Your first infusion, hour by hour — preparation, the experience, and recovery.
How It Works →
The science: the glutamate surge and the dendritic spine regrowth seen in research.
What Is Ketamine Therapy? →
The complete beginner’s guide: history, mechanism, safety, and evidence.
Veterans & the VA →
How VA coverage works for Spravato and IV ketamine, and the Community Care path.
Ketamine FAQ →
Every common question about ketamine in Jacksonville, answered in one place.
Side Effects & Safety →
What to expect: nausea, dizziness, dissociation, blood pressure — and who shouldn’t use ketamine.
The Experience →
Does ketamine get you high? Honest answers about what an infusion actually feels like.
Preparation Guide →
What to eat, what to avoid, what to bring, and how to set yourself up for the best experience.
Aftercare Guide →
First 24 hours, the week after, and how to maximize the neuroplasticity window.
Treatment Protocol →
The standard 6-infusion induction series, why a series matters, and maintenance scheduling.
Ketamine for OCD →
For obsessive-compulsive disorder: how ketamine’s glutamate mechanism may interrupt the OCD loop.
Ketamine for Bipolar Depression →
When antidepressants can’t be used — how ketamine differs for bipolar patients on mood stabilizers.
Ketamine vs. ECT →
How IV ketamine compares to electroconvulsive therapy — efficacy, side effects, and logistics.
Success Rates & Evidence →
What the research actually shows: response rates, remission rates, and what the numbers mean.
Patient Stories →
Real patient experiences with ketamine therapy at The Practice — depression, PTSD, and chronic pain.
Know your exact cost before you commit
Consultations are $49 — not free. The fee is applied toward treatment if you continue, and refunded only if we determine you are not a candidate. Review your history with the provider who would treat you, get an honest recommendation, and leave with your exact treatment cost in writing.
or call (904) 877-1100
