San Marco · Jacksonville, Florida

Medicine with someone in your corner

Founded by a board-certified psychiatric nurse practitioner who believes the best outcomes start with being genuinely known. Psychiatry, ketamine therapy, hormones, and aesthetics — under one roof in San Marco.

Explore our services →

Veteran-owned LegitScript certified Board-certified psychiatric providers

Charles Maddix, MSN, APRN, PMHNP-BC, founder of The Practice in Jacksonville

Charles Maddix, MSN, APRN, PMHNP-BC

Provider & Founder

55%

median response rate for IV ketamine across 12 systematic reviews

24 hrs

many patients feel relief within a day of their first infusion

7

disciplines under one roof, coordinated around your goals

About The Practice

A sanctuary for your wellbeing

The Practice supports mental, emotional, and physical health through compassionate, evidence-based care. Our team combines psychiatric excellence, medical expertise, and modern wellness treatments to help each patient feel seen, supported, and guided.

Holistic Approach

Treating the whole person, not just symptoms. We integrate mind, body, and spirit to foster true, lasting wellness.

Compassionate Care

A safe, non-judgmental space for your healing journey. You are seen, heard, and supported.

Evidence-Based

Modern treatments grounded in clinical science. We stay current with research to offer you the best care.

Meet your providers →
The warm, home-like lobby at The Practice in San Marco, Jacksonville

Designed to feel nothing like a clinic

Our lobby in San Marco.

★★★★★
“Charles Maddix is wonderful and literally saved my life. In just short of a week of a year of seeing him my multiple mental illness issues that were running my life and suffocating me have eased to 50%. That’s a gigantic distance.”
T. D. Google review
★★★★★
“Wouldn’t go anywhere else. Charles Maddix does a great job at making you feel comfortable. He has helped me find the medications that help me function. I look forward to seeing the staff at The Practice. Makes you feel like a part of the team but very professional.”
S. G. Google review
★★★★★
“I have been going to The Practice for almost 8 years. They have ALWAYS been professional. All the doctors are very attentive. They listen to you and work with you. The good thing — the doctors are very honest with you. I love them ALL.”
A. P. Google review
★★★★★
“Great clinicians. Highly recommend. Charles is always attentive to my needs. Very happy with the care I receive.”
N. L. Google review
★★★★★
“Dr. Maddix is an amazing psychiatrist — truly caring, thorough, and attentive. He goes above and beyond to listen and find the best treatment options. I’ve felt genuinely supported, and it’s made a huge difference in my care.”
S. G. Google review
★★★★★
“I have never experienced such amazing, truly compassionate care. They have taken incredible care of me and supported me through so many changes. You can genuinely feel how much they care about their patients. I would highly recommend this practice to anyone and everyone.”
N. M. Google review
★★★★★
“I have been seeing Charlie for a while and both he and the staff genuinely care about their patients and it shows. Excellent clinician and even better people!”
T. G. Google review
★★★★★
“Everyone that works there is great! Mr. Z up front is always helpful and respectful and just a pleasant person all around. Dr. Maddix is a great listener and has an awesome bedside manner. If you choose to go here you will not be disappointed.”
H. C. Google review
★★★★★
“A vibrant new generation of medical professional bringing you into the future you. There are multiple services offered. Dr. Maddix can help guide you on a journey to live a happier lifestyle while exceeding expectations in the needs of mental health support and care.”
S. C. Google review
★★★★★
“The staff here provided a safe and comfortable environment for my sessions. Eased any anxiety and nervousness I felt coming in. Overall, a professional and nurturing program. Would definitely recommend.”
B. R. Google review
★★★★★
“I’ve been going to The Practice for 5+ years. They have always treated me with the utmost kindness and professionalism. I would highly recommend these folks to anyone in need.”
D. G. Google review
★★★★★
“I have been a patient of Charles Maddix and his team for more than 4 years now. I’ve never had anything short of an excellent, professional and helpful experience! Charles and the rest of his team are very knowledgeable and have gone the extra mile many times for me as a patient.”
M. M. Google review
★★★★★
“I have been seeing Charlie Maddix for quite a few years. Very good and he’s very knowledgeable and has helped me with my issues. I would and have recommended him to others.”
D. C. Google review
★★★★★
“The staff at The Practice are extremely welcoming and helpful. I was impressed by all that they offer. Would highly recommend to check them out!! You won’t be disappointed.”
A. G. Google review
★★★★★
“The doctor is great. He has spent extra time with me when he feels I need it. Good staff as well.”
C. F. Google review
★★★★★
“I am so pleased with the level of professionalism Dr. Soto has shown throughout the 15 years I have been under his care. He is always available and treats me with respect and understanding. The virtual appointments are a Heaven sent. I thank God for him and his practice.”
B. B. Google review
★★★★★
“Dr. Acosta is a good Dr. And he is very respectful, courteous, knowledgeable, and professional and he gets to the root of your problems. He sits down with you and listens to your problems, then he gives you his professional opinion.”
E. F. Google review
★★★★★
“I absolutely adore Dr. Soto-Acosta. He really gets to know you and understand your issues.”
C. M. Google review
★★★★★
“Dr. Soto-Acosta and all the staff are always wonderful! I appreciate them all.”
J. B. Google review
★★★★
“Have been coming to The Practice for almost a year now. The staff has always been helpful to me. Dr. Maddix always is willing to listen to my needs and works with me on my medications. I would recommend The Practice if you are struggling with a mental health issue.”
R. C. Google review
★★★★
“Charles is a wonderful physician even if he often leaves you waiting, the whole atmosphere is inviting and welcoming. 4/5.”
J. J. Google review

How it works

Begin with a conversation

  1. 01

    Book a $49 consultation

    Meet our clinical team, review your history and goals, and ask anything. No obligation to continue.

  2. 02

    Receive your plan

    A personalized treatment plan across whichever disciplines serve you — psychiatry, infusions, hormones, or several together.

  3. 03

    Start care that fits

    Unhurried appointments, private treatment rooms, and a team that coordinates around you.

Why choose The Practice

Personalized care in a place built for healing

Veteran-Owned

Trusted local care with disciplined clinical standards and a service-driven approach.

San Marco Location

A calm, accessible wellness destination in Jacksonville's San Marco district.

Integrated Care

Mental health, medical wellness, aesthetics, and vitality services under one roof.

Personalized Treatment

Care plans tailored to each patient's goals, comfort, and clinical needs.

Frequently asked questions

Questions about The Practice

Is the $49 consult refundable?

Yes. If we're not the right fit for your needs, your $49 consultation fee is refunded. If you decide to move forward with treatment, the fee is applied toward your care.

What happens during the first consultation?

Your consultation includes a comprehensive discussion of your symptoms, goals, and medical history. Our team will assess fit and recommend a personalized care path based on your needs.

Is ketamine therapy right for me?

Ketamine therapy may be appropriate for individuals with treatment-resistant depression, anxiety, PTSD, or certain chronic pain conditions. Eligibility is determined through a thorough consultation with our clinical team.

Do you offer care for anxiety, PTSD, and depression?

Yes. We offer comprehensive mental health care including psychiatry, psychotherapy, and ketamine therapy for depression, anxiety, PTSD, and related conditions.

Do you offer both mental health and aesthetics services?

Yes. The Practice provides integrated care across mental health, medical wellness, aesthetics, hormone care, and weight loss support — all under one roof.

Where are you located?

We are located in the San Marco district of Jacksonville, Florida. Our clinic is designed to be a calm, accessible wellness destination.

Do you offer financing?

We can discuss payment options during your consultation. Some services may be covered by insurance. Contact us to learn more about financing options.

How do I schedule as a current client?

Current clients can schedule appointments through our patient portal or by calling the office directly at (904) 877-1100.

Begin here

Start with a $49 consultation

A $49 consultation — get your questions answered by our clinical team. Refunded if we're not the right fit.