Testosterone Replacement Therapy in Jacksonville, FL
TRT without the subscription treadmill
One $799 pellet insertion covers 3–4 months of steady, bio-identical testosterone — no weekly self-injections, no membership fees, and no treatment until your labs say it’s warranted. From the clinic that treats hormones, mood, and men’s health as one connected system.
3547 Hendricks Ave, Jacksonville, FL 32207 · San Marco
TRT at The Practice, at a glance
The facts, before the pitch
- Cost
- $799 per pellet insertion — pellets, procedure, and initial follow-up included
- Cadence
- One in-office visit every 3–4 months; no weekly injections
- Method
- Bio-identical testosterone pellets placed under the skin
- First step
- Comprehensive labs and a clinical evaluation — treatment only if labs support it
- Location
- 3547 Hendricks Ave, San Marco, Jacksonville, FL 32207
- Membership
- None. No subscription, no contract
Sound familiar?
Low testosterone rarely announces itself
It shows up as a slow drift — less energy, less drive, less of yourself. And here’s what most TRT clinics miss: these symptoms overlap heavily with mood, sleep, and stress. Because The Practice was founded by a board-certified psychiatric nurse practitioner, the provider reading your labs can actually tell the difference — and treat whichever it is, under the same roof.
- Persistent fatigue that sleep doesn’t fix
- Low libido or performance changes
- Brain fog and flagging motivation
- Loss of strength or muscle despite training
- Stubborn body-fat gain
- Irritability or flat mood
Pellets vs. injections vs. gels
How the delivery method changes your life on TRT
The hormone is the same. What differs is how steadily it reaches your bloodstream — and how much of your week it takes to manage.
| Pellets (our approach) | Weekly injections | Daily gels & creams | |
|---|---|---|---|
| Hormone levels | Steady daily micro-dose | Peaks after injection, troughs before the next | Varies with absorption and application |
| Your effort | One office visit every 3–4 months | Self-inject every week | Apply every day; avoid skin transfer to family |
| Mood & energy swings | Minimal — levels stay consistent | Common near end of cycle | Possible with missed or uneven doses |
| Typical side-effect profile | Reduced peak-related effects | Peak-related irritability, acne, fluid retention | Skin irritation; transfer risk |
Want the full pellet-therapy deep dive? See our testosterone replacement guide.
Labs first, always
How TRT starts here
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01
Labs first
A comprehensive panel establishes your baseline testosterone and related markers. No labs, no treatment — candidacy is confirmed before anything is scheduled.
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02
Clinical evaluation
Your results are read alongside your symptoms and history — not against a marketing target. If TRT isn’t appropriate, we tell you.
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03
In-office insertion
A ~15-minute procedure at our San Marco clinic. Local anesthetic, a small insertion in the upper hip area, and you drive yourself home.
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04
Monitor and repeat
Follow-up labs track your response. Most men return every 3–4 months for replacement — that’s the entire maintenance routine.
Your provider
Charles Maddix, MSN, APRN, PMHNP-BC
Founder of The Practice and lead for hormone and regenerative medicine. A veteran, Charles built the clinic on a simple idea: lab-guided care, honest recommendations, and mental, physical, and hormonal health treated under one roof.
Meet Charles →Serving all of Northeast Florida
One San Marco clinic, four visits a year
Because pellet therapy only needs an office visit every 3–4 months, men drive in from across the region.
Common questions
TRT in Jacksonville, answered plainly
How much does testosterone replacement therapy cost in Jacksonville?
At The Practice, testosterone pellet insertion for men is $799 — which includes the bio-identical pellets, the in-office procedure, and initial follow-up monitoring. One insertion covers roughly 3–4 months, and there is no membership or subscription fee. (Pellet insertion for women is $499, through our women’s health program.) Labs and consultations are often covered by insurance.
Who provides TRT at The Practice?
Hormone and regenerative medicine at The Practice is led by Charles Maddix, MSN, APRN, PMHNP-BC, the clinic’s founder. Every plan starts with comprehensive labs and a clinical evaluation at our San Marco, Jacksonville clinic.
How is this different from the TRT subscription clinics?
Many testosterone clinics run on weekly injections and monthly membership fees. We use pellet therapy: one in-office insertion every 3–4 months delivers a steady daily dose with no peaks, no troughs, and no recurring subscription. You pay per insertion, and only after labs confirm you’re a candidate. And because your provider oversees hormones, mood, sleep, and weight together, symptoms that aren’t hormonal don’t get force-fit into a testosterone protocol.
How do I know if I actually have low testosterone?
Only lab work can confirm it. Symptoms like fatigue, low libido, brain fog, and loss of strength are suggestive but not diagnostic. We order a comprehensive panel and interpret it against your symptoms — if your levels don’t support treatment, we say so.
How fast will I feel a difference?
Most men notice changes in energy, mood, and libido within a few weeks of their first insertion, with fuller effects developing over the following one to two months as levels stabilize.
Does insurance cover TRT in Jacksonville?
Insurance commonly covers the diagnostic side — labs and consultations — while the $799 pellet insertion is self-pay at our clinic. We walk through pricing and options at your evaluation before anything is scheduled.
Is TRT safe?
Under medical supervision with lab monitoring, testosterone therapy is well studied and generally well tolerated. Pellets in particular avoid the injection-related peaks associated with irritability, acne, and fluid retention. Your evaluation screens for conditions that would make TRT inappropriate.
Where is your TRT clinic located?
The Practice is at 3547 Hendricks Ave in San Marco, Jacksonville, FL 32207 — minutes from Downtown via I-95, and an easy drive from Southside, Mandarin, Riverside, Orange Park, and the Beaches.
More care in Jacksonville
Find out what your labs actually say
Book a TRT consult in San Marco. If your levels don't support treatment, we'll tell you — and if they do, one visit every few months handles the rest.
or call (904) 877-1100