Limited-time offer: ketamine consultations are currently FREE. In person or via Zoom.
Veteran? See how the VA covers ketamine treatment — read our guide.
Ketamine Infusion Therapy in Jacksonville, FL
When other treatments have not brought the relief you need
If you have tried multiple medications or therapies without significant improvement, ketamine infusions may offer a different approach. Many patients seeking ketamine therapy in Jacksonville have experienced treatment-resistant symptoms that impact their daily lives, relationships, and sense of wellbeing.
About this treatment
Clinically guided ketamine infusion therapy
Ketamine is an FDA-approved anesthetic that, when administered at lower than anesthetic doses in a controlled medical setting, may help with treatment-resistant depression, anxiety, PTSD, and certain pain conditions. Our infusions are only administered by advanced practice nurse practitioners who are board-certified in psychiatry or a board-certified psychiatrist in a comfortable, monitored environment. Treatment protocols are personalized based on your consultation, symptoms, and clinical needs.
Why patients choose us
What makes our care different
Ketamine is an FDA-approved anesthetic that, when administered at lower than anesthetic doses in a controlled medical setting, may help with treatment-resistant depression, anxiety, PTSD, and certain pain conditions. Our infusions are only administered by advanced practice nurse practitioners who are board-certified in psychiatry or a board-certified psychiatrist in a comfortable, monitored environment. Treatment protocols are personalized based on your consultation, symptoms, and clinical needs.
Rapid Symptom Relief
Some patients report improvements within hours to days, unlike traditional medications that may take weeks.
Treatment-Resistant Cases
Designed for those who have not found adequate relief from other treatments.
Monitored Sessions
Every infusion is supervised by board-certified psychiatric providers in a controlled medical environment.
Personalized Protocols
Treatment plans are tailored to your specific symptoms, history, and clinical needs.
Multiple Applications
May help with depression, anxiety, PTSD, and certain chronic pain conditions.
Supportive Environment
Our clinic is designed to be calming, comfortable, and conducive to healing.
What to expect
Your path, step by step
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01
Book Your Consult
Choose the service that matches your goals and schedule a consultation.
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02
Meet With Our Team
Discuss your symptoms, history, and treatment options with our clinical team.
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03
Receive a Personalized Plan
Your care path is tailored to your needs, eligibility, and clinical recommendations.
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04
Begin Care With Support
Move forward with a clear plan and ongoing support from The Practice team.
This may be a fit if you…
- Adults seeking personalized, evidence-based care
- Those looking for a comprehensive, whole-person approach
- Patients willing to engage in an initial consultation
- Individuals seeking compassionate, professional healthcare
It may not be right if you…
- Those seeking emergency or acute crisis care (please call 911)
- Individuals unable to participate in the consultation process
- Certain medical conditions may require clearance from your primary physician
What the research shows
IV ketamine vs. Spravato
Systematic reviews of separate controlled trials have reported larger pooled short-term effects for IV ketamine on several measures. These are indirect comparisons — direct head-to-head evidence remains limited.
Key — how to read the numbers
- RR
- Relative Risk — how many times more likely patients were to improve on the treatment than on a placebo (a dummy treatment). Example: RR 3.0 means about 3× more likely to respond. Higher is better.
- Hedges’ g
- A research score for how big the improvement was, not just whether it happened. Rough guide: ~0.2 = small, ~0.5 = medium, ~0.8 or higher = large. Higher is better.
- NNT
- Number Needed to Treat — how many people need this treatment for one extra person to improve compared with placebo. Example: NNT 3 means treat 3 people for one additional good outcome. Lower is better.
Response compared with placebo
Pooled relative likelihood of a clinically meaningful reduction in depression symptoms
RR 3.01
Larger pooled relative effect
RR 1.38
Remission compared with placebo
Pooled relative likelihood of reaching few or no remaining depression symptoms
RR 3.70
Larger pooled relative effect
RR 1.47
Pooled symptom improvement
Standardized effect size across separate controlled trials; study designs and populations varied.
Hedges’ g 1.52
Larger pooled effect size
Hedges’ g 0.31
Number needed to treat (NNT)
Lower NNT means fewer people need treatment for one additional person to respond compared with placebo.
✓ NNT 3 from day 1 to week 1; NNT 9 at 4 weeks
— NNT 2 at day 1; NNT 11 at 4 weeks
Sources: Bahji et al. (2021) Seshadri et al. (2024) Calder et al. (2024) . Figures are relative effects versus placebo or pooled effect sizes from systematic reviews and meta-analyses of depression trials.
Individual results vary. Ketamine therapy is not appropriate for everyone — candidacy is determined during a comprehensive psychiatric evaluation.
Invest in your mind
Flexible options designed for rapid relief and lasting change
6-Pack Series
$449 per infusion
Most common starting protocol
- Six infusions over about 4 weeks
- Private infusion room, every visit
- Board-certified psychiatric provider
- Continuous vitals monitoring
10-Pack Series
$399 per infusion
Best value for extended care
- Ten infusions — induction plus maintenance
- Private infusion room, every visit
- Board-certified psychiatric provider
- Continuous vitals monitoring
Single Booster Infusion
$549 per infusion*
For returning patients
- One infusion at your established dose
- Private infusion room
- Board-certified psychiatric provider
- Continuous vitals monitoring
Pricing applies to ketamine infusions for depression, anxiety, and PTSD. Infusions for chronic pain are priced separately — pain protocols require nearly three times the treatment time.
Package pricing represents per-infusion cost when purchased as a series. Financing options available — ask during your consultation.
*Only clients who have already completed an induction protocol (6 infusions in 4 weeks) with The Practice may book single infusions.
See the full cost breakdown — financing, insurance & Spravato comparison →
Common questions
What patients ask about Ketamine Therapy
What conditions can ketamine therapy help with?
Ketamine therapy may help with treatment-resistant depression, anxiety, PTSD, and certain chronic pain conditions. Eligibility is determined through a comprehensive consultation with our clinical team.
What does a ketamine infusion session feel like?
Most patients describe a relaxed, dream-like state. You remain conscious throughout the session in a comfortable, monitored setting. Our team ensures you feel safe and supported at every step.
How many sessions are typically needed?
Treatment protocols vary by individual. Many patients begin with a series of sessions, followed by maintenance treatments. Your specific plan is personalized during your consultation.
Is ketamine therapy safe?
Ketamine has been used safely in medical settings for decades. Our infusions are only administered by advanced practice nurse practitioners who are board-certified in psychiatry or a board-certified psychiatrist, in a controlled, monitored environment with appropriate safety protocols.
How should I prepare for my infusion?
You will receive detailed preparation instructions before your first session. Generally, we recommend avoiding food for a few hours beforehand and arranging transportation home.
Are there any side effects?
Some patients may experience mild, temporary effects such as drowsiness or nausea. Our team monitors you throughout and is prepared to manage any discomfort.
Will my insurance cover ketamine therapy?
Coverage varies by provider and plan. Our team can help you understand your options and provides documentation that may support insurance claims.
How soon might I notice results?
Some patients report feeling improvements within hours to days after their first session. Results vary by individual and condition being treated.
From our blog
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Spravato VS Ketamine
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The ketamine resource center
Keep exploring ketamine therapy
Treatment-Resistant Depression →
When two or more antidepressants haven’t worked — what ketamine offers TRD.
Ketamine for Anxiety →
Rapid relief for persistent anxiety, panic, and nervous-system activation.
Ketamine for PTSD →
Trauma-informed infusion care for hypervigilance and flashbacks.
Ketamine for Chronic Pain →
CRPS, neuropathy, migraines, and centralized pain protocols.
Cost & Pricing →
Transparent pricing: $399–$549 per infusion, financing, and insurance notes.
Ketamine vs. Spravato →
How IV ketamine and the FDA-approved nasal spray compare on results and cost.
What to Expect →
Your first infusion, hour by hour — preparation, the experience, and recovery.
How It Works →
The science: the glutamate surge and the dendritic spine regrowth seen in research.
What Is Ketamine Therapy? →
The complete beginner’s guide: history, mechanism, safety, and evidence.
Veterans & the VA →
How VA coverage works for Spravato and IV ketamine, and the Community Care path.
Ketamine FAQ →
Every common question about ketamine in Jacksonville, answered in one place.
Explore treatments
More care at The Practice
Find out if ketamine therapy is right for you
For a limited time, ketamine consultations are free — in person or via Zoom. Get your questions answered by our clinical team at no cost.